DR. MACRENE actives is a luxury skincare brand focused on anti-wrinkle and high-performance skincare products. Founded by Dr. Macrene Alexiades MD PhD, a board-certified dermatologist and molecular scientist, the brand specializes in plant-based, clean beauty formulations powered by patented multi-active technology (MA37™). The product range includes cleansers, face creams, serums, tinted moisturizers, and lip fillers that are cruelty-free, vegan, gluten-free, and formulated without harmful chemicals. The brand emphasizes sustainable packaging using glass, wood, and uncoated paperboard printed with vegetal inks. DR. MACRENE actives offers spa treatments at locations in Manhattan and Wainscott and provides services such as routine finder, subscription, and loyalty programs. The mission of the company is to replace cosmetic procedures with effective topical skincare solutions using scientifically backed natural ingredients.